Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 6 de 6
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Sci Adv ; 9(35): eadh8619, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37656783

RESUMO

Phototherapeutics has shown promise in treating various diseases without surgical or drug interventions. However, it is challenging to use it in inner-body applications due to the limited light penetration depth through the skin. Therefore, we propose an organic light-emitting diode (OLED) catheter as an effective photobiomodulation (PBM) platform useful for tubular organs such as duodenums. A fully encapsulated highly flexible OLED is mounted over a round columnar structure, producing axially uniform illumination without local hotspots. The biocompatible and airtight OLED catheter can operate in aqueous environments for extended periods, meeting the essential requirements for inner-body medical applications. In a diabetic Goto-Kakizaki (GK) rat model, the red OLED catheter delivering 798 mJ of energy is shown to reduce hyperglycemia and insulin resistance compared to the sham group. Results are further supported by the subdued liver fibrosis, illustrating the immense potential of the OLED-catheter-based internal PBM for the treatment of type 2 diabetes and other diseases yet to be identified.


Assuntos
Diabetes Mellitus Tipo 2 , Hiperglicemia , Animais , Ratos , Catéteres , Diabetes Mellitus Tipo 2/terapia , Duodeno , Hiperglicemia/terapia , Fototerapia
2.
Sci Rep ; 12(1): 9506, 2022 06 09.
Artigo em Inglês | MEDLINE | ID: mdl-35681067

RESUMO

We propose two novel methods to effectively utilize parylene C films. First, we demonstrate a vertical deposition method capable of depositing a parylene C film of the same thickness on both sides of a sample. Through this method, we have formed parylene C films with a thickness of 4 µm on both sides of the sample with a thickness deviation of less than 2.5%. Further optical verification indicates that parylene C films formed by this method have a very uniform thickness distribution on each side of the surfaces. Second, we propose a debris-tolerant laser patterning method as a mask-less means to fabricate self-supporting ultrathin parylene C films. This method does not involve any photolithography and entails a simple and rapid process that can be performed using only a few materials with excellent biocompatibility. It is demonstrated that patterned parylene C films exhibit a high degree of surface uniformity and have various geometrical shapes so that they can be used for substrates of highly flexible and/or stretchable devices. Finally, we use both of the proposed methods to fabricate flexible, stretchable, and waterproof-packaged bifacial blue LED modules to illustrate their potential in emerging applications that would benefit from such versatile form factors.


Assuntos
Polímeros , Xilenos , Lasers
3.
Sci Rep ; 8(1): 15416, 2018 Oct 18.
Artigo em Inglês | MEDLINE | ID: mdl-30337719

RESUMO

Recently, a planoconvex structure electrowetting lenticular lens capable of 2D/3D conversion through a varifocal property by an electrowetting phenomenon has been developed. However, even though it has a similar planoconvex structure to that of a commercial solid lenticular lens, comparable 3D performance could not be realized because the refractive index difference between nonconductive liquid and conductive liquid was not large. Therefore, the goal of the present study is to obtain better 3D performance compared to the conventional planoconvex structure by introducing a novel biconvex structure using ETPTA. The newly developed biconvex structure electrowetting lenticular lens showed greatly improved characteristics compared to the planoconvex structure: dioptric power (171.69D → 1,982.56D), viewing angle (26degrees → 46degrees), and crosstalk ratio (27.27% → 16.18%). Thanks to these improvements, a fine 3D image and a natural motion parallax could be observed with the biconvex structure electrowetting lenticular lens. In addition, the novel biconvex structure electrowetting lenticular lens was designed to achieve a plane lens state with a no voltage applied condition, and as such it could show a clean 2D image at 0 V. In conclusion, a novel biconvex structure electrowetting lenticular lens showed 2D/3D switchable operation as well as excellent 3D performance compared to a solid lenticular lens.

4.
Opt Express ; 26(15): 19614-19626, 2018 Jul 23.
Artigo em Inglês | MEDLINE | ID: mdl-30114132

RESUMO

In this paper, we introduce a method for improving the lens diopter of 2D/3D convertible devices using electro-wetting. For stable operation, an electro-wetting device requires high dioptric performance and this was achieved using bi-convex liquid-liquid-solid phases. 1-Chloronaphthalene with a refractive index of 1.633 was used as an oil phase to achieve high diopters. ETPTA (trimethylolpropane ethoxylate triacrylate), a UV-sensitive material with low chemical reactivity to the 1-Chloronaphthalene, was used as a chamber material. This resulted in a diopter of 3030D for high quality multi-view images without unstable oil movement or trembling. The ETPTA was molded on a 0.3mm thick glass substrate that was coated with UV adhesive (NOA 81). The maximum diopter capable of stable operation was 3425D. 2D and 3D conversion and parallax motion were demonstrated.

5.
Appl Opt ; 56(7): 1886-1892, 2017 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-28248385

RESUMO

While there are many ways to realize autostereoscopic 2D/3D switchable displays, the electrowetting lenticular lens is superior due to the high optical efficiency and short response time. In this paper, we propose a more stable electrowetting lenticular lens by controlling the quantity of oil. With a large amount of oil, the oil layer was broken and the lenticular lens was damaged at relatively low voltage. Therefore, controlling the amount of oil is crucial to obtain the required dioptric power with stability. We proposed a new structure to evenly adjust the volume of oil and the dioptric power was measured by varying the volume of oil. Furthermore, the optical characteristics were finally analyzed in the electrowetting lenticular lens array with a proper amount of oil.

6.
Opt Express ; 24(26): 29972-29983, 2016 Dec 26.
Artigo em Inglês | MEDLINE | ID: mdl-28059382

RESUMO

In this paper, we used a thin polycarbonate (PC) chamber to improve the performance of an electrowetting lenticular lens array. The polycarbonate chamber changed the radius of curvature (ROC) of the oil acting as a lens, which increased the dioptric power of the liquid lens to 1666.7D. The increase in dioptric power required a reduction in the distance between the optical center of the lens and the display pixels under the chamber, which was accomplished by reducing the thickness of the chamber. The optimal thickness of the chamber was determined to be 0.5mm. Using this thin PC chamber, transmittance and viewing angle were measured and compared with an electrowetting lenticular lens with a conventional 1mm poly methyl methacrylate (PMMA) chamber was done. Crosstalk which degrades clear 3D images, is an inevitable factor in lenticular lens type multi-view systems. With the 0.5mm PC chamber, the viewing zone was expanded and the ratio of the crosstalk area was reduced, which resulted in a clear 3D image. The new method of depositing the electrode layer also ensured the uniform operation of the liquid lens array.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...